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KMID : 0363220200580030207
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Korean Journal of Dermatology
2020 Volume.58 No. 3 p.207 ~ p.211
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Case Reports of Spitz Nevus with a Halo Phenomenon
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Choi Myoung-Eun
Lee Woo-Jin
Chang Sung-Eun
Choi Jee-Ho
Lee Mi-Woo
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Abstract
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Halo nevus clinically presents as a nevus with a surrounding ring of depigmentation that histopathologically demonstrates a dense lymphocytic reaction to the melanocytic component of the epidermis. While melanocytic nevi with halo phenomena are common, a halo reaction is uncommon in Spitz nevus. When a halo reaction develops around a Spitz nevus, differential diagnosis from melanoma arising from pre-existing nevus is difficult due to the presence of dense inflammatory components. A halo reaction itself can increase the cytologic atypia of melanocytes and can obscure nest maturation. Herein, we report rare cases of Spitz nevus combined with a halo reaction. It is important to note that the halo phenomenon can occur without a clinically evident white patch and that the architectural features of the nevus components can be used to distinguish Spitz nevus from malignant melanoma.
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KEYWORD
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Halo nevus, Melanoma, Immune response, Spitz nevus
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